Hyperemia & Testosterone Enhancing PWD (Clinically-Studied CFB & Vasoactive Compounds). Highest Concentration (More than 3x Strength): 1-Scoop Potency. Reactive hyperemia describes the increase in muscle blood flow that occurs during high-intensity resistance exercise and produces the 'pump' associated with increases in muscle size. The Nitraflex pretraining formula contains ingredients that in vitro, animal and clinical studies suggest possess properties that may help advanced athletes maximize energy, intensity, vascularity and reactive hyperemia (pumps) during their workouts, and provide long-term support of testosterone and nitric oxide levels in the healthy range when used as directed. Unique Properties of some of the key compounds in Nitraflex: 1-Scoop Potency: Nitraflex is so potent, only 1 scoop (1 serving) is necessary. Do not exceed 1 scoop in a single 24-hour period. Do not take Nitraflex with 5 hours of bedtime. High Citrulline: Arginine Ratio: Arginine is a proven precursor in nitric oxide (NO), a vasodialator. What most people don't know is that Arginine supplementation stimulates the activity of arginase, an enzyme that breaks down Arginine. Over time, this may actually result in reduced Arginine and NO levels in turn causing your preworkout formula to stop working. Research suggests that supplementing with a high ration of citrulline to Arginine may reduce this risk by avoiding overstimulation of arginase. 6 Weeks of Testosterone: Calcium fructopyranose borate (CFB) has been shown to increase testosterone in health subjects. The average increase in total and free testosterone in a 6-week study was 56% and 29.5% respectively. In a second study, total and free testosterone increased on 3 hours after a single dose of CFB. Effective Doses of Beta-Alanine: The clinically-proven performance enhancer beta-alanine was not 'fairy dusted' in this formula. Rather, we added an exceptionally powerful does that you will feel working following your very first serving. Creatine-Free: Creatine causes water retention, which can make achieving a dry, hard muscular look even more difficult. Sometimes creatine is added to products precisely for this reason. (When you see yourself getting bloated, you may be fooled into thinking the product is 'working.') We left it out of Nitraflex precisely for this reason. Cognitive Enhancers: Nitraflex contains unique ratios of scientifically validated compounds that help you remain alert, intense and focused while you're flying from set to set with veins fully dialated and muscles pumped to the hilt.